A self-adjuvanted nanoparticle based vaccine against infectious bronchitis virus.
Infectious bronchitis virus (IBV) affects poultry respiratory, renal and reproductive systems.Currently the efficacy of available live attenuated or killed vaccines against IBV has been challenged.We designed a novel IBV vaccine alternative using a highly innovative platform called Self-Assembling Protein Nanoparticle (SAPN).In this vaccine, B cell